https://www.sec.gov/Archives/edgar/data/906185/000119312518092334/d555678d497.htm497 1 d555678d497.htm 497  
Janus Aspen Series 
Janus Henderson Balanced Portfolio 
Janus Henderson Global Allocation Portfolio - Moderate 
Supplement dated March 23, 2018 
to Currently Effective Prospectuses 
At a special meeting of shareholders of Janus Henderson Global Allocation Portfolio – Moderate held on March 22, 2018, shareholders approved an Agreement and Plan of Reorganization that will result in the transfer of the assets and liabilities of Janus Henderson Global Allocation Portfolio – Moderate to Janus Henderson Balanced Portfolio, effective on or about the close of business on April 27, 2018 (“Closing Date”). As a result, shareholders of Janus Henderson Global Allocation Portfolio – Moderate as of the Closing Date will become shareholders of Janus Henderson Balanced Portfolio, and Janus Henderson Global Allocation Portfolio – Moderate will be terminated.